2017 Strain Variation in the Mycobacterium tuberculosis Complex (pdf)

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Author Sebastien Gagneux (eds.)
Edition 1
Edition Year 2017
Format PDF
ISBN 9783319643717
Language English
Number Of Pages 319
Publisher Springer International Publishing

Description

Until about 10 years ago, the general view in the field was that Mycobacterium tuberculosis, the causative agent of human tuberculosis was a “clone” with insufficient natural sequence variation between clinical strains to be considered biologically and epidemiologically “relevant”. This view has now changed quite dramatically thanks to the –omics revolution, particularly the advent of next generation DNA sequencing. Large-scale comparative genomic studies over the last few years have revealed that M. tuberculosis clinical strains are more genetically diverse than appreciated previously.

Additional information

Author

Sebastien Gagneux (eds.)

Edition

1

Edition Year

2017

Format

PDF

ISBN

9783319643717

Language

English

Number Of Pages

319

Publisher

Springer International Publishing

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